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5-HTP: The Natural Way to Overcome Depression, Obesity, and Insomnia. There is a massive amount of evidence that suggests that low serotonin levels are a common consequence of modern living. The lifestyle and dietary dyspepsia treatment home remedy of many people living in this stress-filled era results in lowered levels of serotonin within the brain. Although 5-HTP may be relatively new to the United States health food industry, it has been available through pharmacies for several years and has been intensely researched for the past three decades.